The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Background
Men with congenital unilateral absence of vas deferens were reported to be mainly azoospermic, with both unilateral renal absence and mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) but some have neither.
Objectives
To assess whether in infertile couples the male partners with congenital unilateral absence of vas deferens are mainly azoospermic men.
Material...
Background
Despite the well‐known influence of psychological and situational factors on erectile dysfunction, the influence of the physician's gender on the andrological workup has never been investigated so far.
Objectives
To investigate physician's gender influence on the erectile dysfunction diagnostic workup.
Materials and methods
Cross‐sectional study with retrospective data collection....
Background
Cholesterol import into the mitochondria of steroid‐producing cells is the rate‐determining step in steroidogenesis. Numerous studies have provided evidence that the cholesterol‐binding translocator protein (18 kDa TSPO) plays an important role in cholesterol translocation into mitochondria and that it also might act on cholesterol homeostasis. Several TSPO‐specific ligands have been shown...
Background
In infants, fever is often treated with acetaminophen or ibuprofen, two antipyretic and analgesic drugs inhibiting cyclooxygenases (COXs), enzymes catalyzing prostaglandin production. Infancy represents a critical developmental period when neonatal germ cells/gonocytes differentiate to spermatogonial stem cells required for spermatogenesis.
Objectives
(a) Determine the expression of...
Background
The potential toxicity that results from environmental xenobiotics is not completely known. Increasing levels of heavy metals and the use of organophosphate pesticides (OPs) and their co‐existence in the environment could be associated with an increasing incidence of male reproductive system disorders in humans and animals. Ferulago angulata is a dietary source of phenolic compounds with...
Background
The paternal role in embryogenesis is much more than providing a haploid genome. The spermatozoa have crucial roles related to embryogenesis' epigenetic regulation, fusion of gametes, and cleavage, which may influence intracytoplasmic sperm injection outcomes.
Objectives
To study whether paternal age, length of ejaculatory abstinence and semen parameters influence the outcomes of intracytoplasmic...
Background
Diabetes mellitus is one of the risk factors for male subfertility/infertility. Malaysian propolis is reported to decrease hyperglycaemia in diabetic state.
Objectives
The present study investigated the protective effect of Malaysian propolis on diabetes‐induced subfertility/infertility. Additionally, its combined beneficial effects with metformin were investigated.
Materials and methods...
Background
Androgen deprivation therapy (ADT) is widely being applied in men who suffered from prostate cancer. Whether androgen deprivation therapy (ADT) is associated with an increased risk of developing cardiovascular‐related disease is poorly defined.
Objectives
The aim of the present meta‐analysis is to explore the relationship between ADT and the risk of cardiac events.
Materials and methods...
Background
At the beginning of the 20th century, the Viennese physiologist Eugen Steinach proposed to treat the effects of physiological ageing by vasectomy. After experimenting his theory with animal, he published his results, and convinced scientists to apply this method to humans (ie men). The scientific community has been convinced by these pictures of the interest of these vasectomies, and many...
Background
Molecules from the female reproductive tract modulate capacitation and function of sperm cells in vivo. These molecules vary in a quantitative and qualitative manner throughout the estrous cycle.
Objectives
This work evaluates the effect of using various female reproductive fluids on capacitation and fertilization of pig spermatozoa in vitro.
Material and methods
The effects of culturing...
Background
The management of male idiopathic infertility is heterogeneous. Although meta‐analyses reported the effectiveness on pregnancy rate, the real clinical impact of follicle‐stimulating hormone (FSH) was not evaluated so far. In Italy, FSH is approved by the National Medicines Agency (AIFA) for idiopathic infertile patients with FSH < 8 IU/L, independently of semen parameters.
Aim
Primary...
Background
A recent meta‐analysis (Human Reproduction Update 23, 2017 and 265) reported positive sperm retrieval rates (SRR) in 50% of patients with Klinefelter syndrome (KS) undergoing testicular sperm extraction (TESE). However, these results do not reflect the rates of SR that we observe in clinical practice. We assessed the rate and potential predictors of SR in Klinefelter patients in the real‐life...
Background
Metformin, a drug used to treat type 2 diabetes, has gained attention for its multiple therapeutic applications. However, little is known about its effects on human sperm function at therapeutically relevant concentration.
Objectives
The aim of this study was to elucidate the in vitro actions of metformin on human sperm function and explore the underlying mechanism of any effects.
...
Background
Functional hypogonadism is a common disorder among patients with obesity and type 2 diabetes mellitus and could be managed by first treating the underlying causes.
Objective
The present study was undertaken to investigate the contribution of body weight and glycemic control to the reversibility of hypogonadism to eugonadism in a real‐life setting.
Materials and methods
Adult obese...
Background
Diabetes mellitus (DM) induces impairment of male reproductive system and is considered as a key factor that could partially provide an explanation for male infertility. Thus, understanding the mechanism underlying DM‐induced infertility will aid in the identification of novel therapeutic stratagems.
Objectives
To delineate the role of ROS/JAK2/NFκB pathway in DM‐induced low reproductive...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.